Abstract
Polymorphism of the B subunit of human coagulation factor XIII was investigated in a total of 119 plasma samples from unrelated adult Japanese using agarose gel electrophoresis followed by immunofixation. Three common phenotypes were observed, which corresponded to the types 1, 1–3 and 3 reported by Board (1980) in Australians. The estimated allele frequencies ofF13B*1 andF13B*3 were 0.303 and 0.697, respectively. The observed numbers of the phenotypes were in good agreement with those expected on the basis of Hardy-Weinberg's law. These results are not inconsistent with the hypothesis that these phenotypes are controlled by a pair of autosomal, codominant alleles.
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Schedule a callMore From: Jinrui idengaku zasshi. The Japanese journal of human genetics
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