Abstract
Genetic data was obtained in a sample from Macau using an X-STR decaplex system. Allele frequencies were calculated for all loci. Observed genotype distributions did not show deviations from Hardy–Weinberg expectations. DXS6809 was the most polymorphic marker in Macau while DXS7133 was the least discriminating. Single locus comparisons with other Asian populations showed significant genetic distances with Pakistan, Japan, Mongolia and Korea. With samples from Taiwan and US Asians no significant genetic differences were obtained. No significant association was found between any of the pairs studied after applying Bonferroni's correction ( p < 0.001). However, low p values were found between DXS6809 and DXS6789 ( p = 0.0030) and DXS8378–DXS9902 ( p = 0.0035) that belong to two described STR clusters on the X chromosome. The decaplex system used in this work was evaluated for potential application in human identification and kinship testing in the present population: high overall values of power of female (99.9999995%) and male (99.998%) discrimination were obtained, as well as high overall values of power of exclusions in father/mother/daughter trios (99.996%), in father/daughter duos (99.92%) and in half-sisters with same father (98%).
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