Abstract
The genetic component must be considered as one of the mechanisms responsible for some types of cerebral palsy. Fifty of the 100 cases here reviewed were of prenatal origin. Eleven cases had a developmental etiology and 32 were due to prematurity. In the perinatal group 24 cases were due to anoxia. These etiological factors are the least understood, and the present investigation indicates that some genetic mechanism is involved. It was found that the sex ratio of the normal siblings was one, whereas in the cerebral palsied group there was an excess of boys. Primogeniture was not considered a predisposing factor in cerebral palsy. Incomplete pregnancies, ranging from one to five per family, were present in 30 families. The distribution of blood groups among the 100 patients gave an excess of group A above the expected number.
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