Genetic localization of a follicle cell protein locus in Drosophila melanogaster

Abstract

Three variant forms of a “novel” set of follicle cell proteins (Fc) were found when screening geographic wild-type strains of Drosophila melanogaster by SDS-polyacrylamide gel electrophoresis of 35S-methionine labelled ovaries. These variant forms were used to establish X chromosomal linkage and for further genetic localization by both recombinant analysis and by cytogenetical mapping. A locus involved in the synthesis of Fc proteins was localized to the 7C1-9 region, i.e. very close to the singed locus (21.0 cM). The number of Fc proteins, their variation and possible function is discussed.