Abstract

Alzheimer's disease (AD) is classified as a neurodegenerative disorder that alters the memory and cognitive capacity of the affected individual, in addition to causing behavioral changes and other neuropsychiatric symptoms. In this work, genes involved in the metabolism of this neurodegenerative disorder were reported, as well as their positioning on their chromosomes with an emphasis on the human genome. The following research sources were used to collect data and results: scientific articles, books and websites specializing in this subject regarding AD and the human genome. The result of this investigation indicated that the genes studied are located on chromosomes 1, 14, 17, 19 and 21 in the human genome, and associated with early AD disease in humans. Therefore, the identification of genes related to AD is necessary for a better understanding of AD genetics and also for the development of molecular markers of therapeutic targets for the diagnosis and treatment of this dementia.

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