Abstract
Schistosomiasis is a chronic and debilitating disease especially in developing countries. S. haematobiumof the urinogenital system is a major human health problem across Africa. Geneticvariability recommended studying variation in disease burden and pathology, and epidemiologicalaspects. The present study investigated genetic diversity and polymorphism human S. S.haematobium isolated by using RAPD-PCR technique on 50/100 urine samples from differentareas in Sohag Governorate.Extracted DNA was used for molecular analysis using RAPD-PCR primers (A01, A02, A12,A13, & Y20). 27 S. haematobium DNA isolates (54%) were amplified by using specific primers.The isolates showed distinct variation in size and number of amplified fragments, indicatinghigh genetic variation among them.
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