Abstract

TARCH or agar gel electrophoresis coupled with azo dye staining methods has permitted the detection of genetically determined variants of several forms of nonspecific carboxylic esterases in a protozoan (ALLEN 1961), maize ( SCHWARTZ 1960, 1964), Drosophila (WRIGHT 1963; WRIGHT and MACINTYRE 1963), and house flies (VELTHUIS and VAN ASPEREN 1963). In mammals, inherited electrophoretic variants of esterases have been reported from the serum (POPP and POPP 1962; PETRAS 1963) and kidney (RUDDLE and RODERICK 1965) of the house mouse ( M u s musculus), and from red cell lysates of the deer mouse (Peromyscus maniculatus) (RANDERSON 1964) and of man (TASHIAN 1965). The present report describes the genetic control, and preliminary chemical characterization, of some electrophoretic forms of nonspecific esterases in hemolysates of the house mouse.

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