Abstract
We isolated Japanese encephalitis virus genotype 5 from human specimens in South Korea. Whole-genome analysis showed 90.4% identity with other genotype 5 viruses from humans. This virus had a unique insertion in the NS4A gene. However, the envelope protein contained Lys 84, which was specific to strains of genotype 5 viruses from South Korea.
Highlights
We isolated Japanese encephalitis virus genotype 5 from human specimens in South Korea
By estimating the root of the time measured on the E gene of Japanese encephalitis virus (JEV) genotype 5 viruses, we identified that the XZ0934 strain from Tibet was an ancestor of JEV genotype 5 virus strains from South Korea (Figure 2, panel C)
JEV genotype 5 was isolated from mosquitoes in China during 2009 and South Korea during 2010
Summary
We isolated Japanese encephalitis virus genotype 5 from human specimens in South Korea. Genotype 5 was identified in mosquitoes in South Korea [3]. JEV genotype 5 has been detected in mosquitoes in many areas of South Korea [4]. We report isolation of JEV genotype 5 virus from patient specimens and differences in sequences among other JEV strains (genotypes 1–5).
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