Abstract
Genetic sequences of a highly pathogenic avian influenza (H5N8) virus in England have high homology to those detected in mainland Europe and Asia during 2014. Genetic characterization suggests this virus is an avian-adapted virus without specific affinity for zoonoses. Spatio-temporal detections of H5N8 imply a role for wild birds in virus spread.
Highlights
COMMISSION DECISION of 4 August 2006 approving a Diagnostic Manual for avian influenza as provided for in Council Directive 2005/94/EC (notified under document number C(2006) 3477)
Having regard to Council Directive 2005/94/EC of 20 December 2005 on Community measures for the control of avian influenza and repealing Directive 92/40/EEC (1), and in particular the second subparagraph of Article 50(1) thereof, (5) The experience gained in the control of avian influenza in recent years has resulted in the identification of the most suitable sampling procedures and criteria for evaluation of the results of the laboratory tests for a proper diagnosis of this disease in different situations
Whereas: (1) Directive 2005/94/EC provides for certain preventive measures relating to the surveillance and early detection of avian influenza and minimum control measures to be applied in the event of an outbreak of that disease in poultry and other captive birds
Summary
(a) guidelines and minimum requirements for diagnostic procedures, sampling methods and criteria for the evaluation of the results of laboratory tests for a proper diagnosis of AI;. 4. The confirmation of AI in poultry and other captive birds must be in accordance with the procedures, sampling methods and criteria for the evaluation of the results of laboratory tests set out in this diagnostic manual, and be based on one or more of the criteria in points (a), (b) and (c):. (a) the detection of infectious virus, antigen or specific genetic material in samples of poultry or other birds' tissues, organs, blood or excreta;. (a) the detection of the AI infectious virus, antigen or specific genetic material in samples of tissues, organs, blood or excreta from mammals;. (i) the sensitivity and specificity of the authorised laboratory tests have been demonstrated as being effective following a comparative test organised by the Community reference laboratory for avian influenza (Community reference laboratory); or (ii) where no such evaluation has been organised by the Community reference laboratory for a specific type of laboratory test, the sensitivity and specificity of the authorised laboratory test have been validated by the national reference laboratory so that the laboratory test is fit for the purpose for which it is used; the results of such validation must be submitted to the Community reference laboratory for review
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