Abstract
Mutants at 2 new loci which control mutagen-sensitivity are described. Mutants at both loci are female-sterile and are hypersensitive to killing by MMS; neither increases the frequency of sex-linked recessive lethals. A screen of previously described female-sterile and meotic mutants has revealed that a number of these are also sensitive to mutagens. In addition, several new mutants have been identified on the basis of sensitivity to either HN2 or MMS. An anlysis of complementation data suggests that all of the X-linked genes controlling sensitivity to MMS may now have been identified. Among the new mei-41 alleles are mutants which show verly little meiotic nondisjunction or loss. Cytogenetic mapping of previously known mutants is also described. The mutants mus(1)104 D1 and mei-41 D5 are located in th eregion 14B13±−14D1,2 on the polytene chromosome map, and they map very close to each other genetically. Cytogenetically mus(1)101 D1 is between salivary chromosome bands 12A6,7 and 12D3, mus(1)103 D1 is between bands 12A1,2 and 12A6,7, and mus(1)-109 A1 is in section 8F3-9A2.
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