Abstract

The experiment was carried out to study the single nucleotide polymorphism of Heat Shock Protein (HSP90AA1) gene in selected Nigerian indigenous cattle in Adamawa State. Blood taken on eighty (80) lactating animals within their early lactation (1-60). HSP90AA1 gene was extracted and sequenced. Eight (8) sequences were generated from the selected breeds and were deposited in the GenBank with accession numbers MZ2355888 – MZ2355895. The sequences generated in this study revealed six (6) polymorphic sites in the coding regions (136 G>A, 136 G>A, 89 C>G, 89 C>G, 86 A>G and 86 A>G) that defined four haplotypes. Analysis of Molecular Variance (AMOVA) of the four breeds revealed that 58.18% of the variation was among breeds than within breeds (41.81%). It was concluded that there is more genetic variation among the studied breeds than within the breeds for HSP90AA1 gene.

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