Abstract
Chinese tongue sole (Cynoglossus semilaevis) is an economically important marine fish in China. Generally, the eyeless side of the Chinese tongue sole is white and the side with eyes is brown after metamorphosis, hypermelanosis may still occur in the eyeless side in certain individuals after metamorphosis, which greatly decreases consumer acceptance and market price. In order to study the possibility of genetic improvement, we determined genomic markers in Chinese tongue sole using the genotyping-by-sequencing method and analyzed their association with hypermelanosis area. Genetic analysis showed that hypermelanosis was a complicated quantitative trait, and the estimated heritability for hypermelanosis incidence and area ratio were 0.16 and 0.21, respectively. Genomic selection analysis showed that selection based on hypermelanosis incidence and area ratio had similar reliabilities and prediction accuracies, indicating the feasibility of genetic improvement. Nine loci were significantly associated with hypermelanosis, few of which included genes or flanked genes potentially associated with skin disease, indicating the potential complicated genetic mechanisms underlying hypermelanosis in the Chinese tongue sole.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
