Abstract
Phenylhydrazine hydrochloride, p-Aminopropiophenone and Methylene blue serve as models for the examination of the temporal connexions between the possible formation of methemoglobin and the appearance of Heinz bodies. It is proved that there is no correlation between the formation of ferrihemoglobin and precipitations in the erythrocytes. These findings and the application of the various substances and the appearance of the Heinz bodies lead to the conclusion, that different mechanisms of the metabolism are responsible for the appearance of the Heinz bodies. The appearance of ferrihemoglobin is not a prerequisite for the presence of precipitations in the erythrocytes but can be observed in certain cases contemporary with or prior to the formation of Heinz bodies.
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