Abstract
Apparently contrasting approaches, ie genetic engineering and screening of new microorganisms, play essential complementary roles to develop current industrial microbiology. Three topics, production and modification of milk-clotting proteinases by genetic engineering, hormonal control of secondary metabolism in streptomycetes, and screening of bioactive metabolites, are introduced as cases of such a hybrid approach, while symbiotic microorganisms are discussed as an example of the vast terra incognita still remaining for the future microbiology.
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