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Abstract
Magnesium-based ceramics are involved in orthopedic applications such as bone scaffolds or implant coatings. They provide structural support to cells for bone ingrowth, but highly porous matrices cannot resist severe mechanical stress during implantation. In this study, the laser floating zone (LFZ) technique is used to prepare a dense crystalline material with composition in the CaO–SiO2–MgO–P2O5 system. This material, under physiological conditions, is able to generate a porous scaffold controlled by the dissolution of the MgO phase, meeting the mechanical advantages of a dense material and the biological features of a porous scaffold. FESEM (Field emission scanning electron microscopy), XRD (X-ray Diffraction), EDS (Energy Dispersive X-rays spectroscopy), and ICP ((Inductively Coupled Plasma) analysis were carried out in order to characterize the samples before and after immersion in simulated body fluid (SBF).
Highlights
The increase in the age of the population carries greater incidence of musculoskeletal pathologies such as fractures, osteoporosis, and bone infection and tumors
The purpose of our work was to develop a new material obtained from the melt with a composition that includes calcium and magnesium phosphate, silicate bioactive phases, and a primary phase of magnesium oxide that forms pores when dissolved in simulated body fluid (SBF), creating the mechanical advantages of a dense material and the biological features of a porous scaffold
1, there are peaks that correspond to periclase (MgO), forsterite (Mg2SiO4), and conducted, obtaining the results shown in Figures 1 and 2, respectively
Summary
The increase in the age of the population carries greater incidence of musculoskeletal pathologies such as fractures, osteoporosis, and bone infection and tumors. Implants and biomedical devices have been used to replace bones and joints, but these solutions are subject to many limitations such as fatigue, fractures, toxicity, and wear. The behavior of these implants and devices do not completely meet the requirements to which bone tissue is subjected [1,2,3]. The success depends on the development of porous matrices (scaffolds) that provide the structural and mechanical support to cells for their attachment and proliferation. The material chosen as a matrix must meet be non-toxic, biocompatible, osteoproductive, osteconductive, and bioabsorbable and have sufficient mechanical properties to provide structural support during bone growth and remodeling [4,5,6]
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