Abstract

We describe an approach to generate a heterosexual network with a prescribed joint-degree distribution embedded in a prescribed large-scale social contact network. The structure of a sexual network plays an important role in how all sexually transmitted infections (STIs) spread. Generating an ensemble of networks that mimics the real-world is crucial to evaluating robust mitigation strategies for controlling STIs. Most of the current algorithms to generate sexual networks only use sexual activity data, such as the number of partners per month, to generate the sexual network. Real-world sexual networks also depend on biased mixing based on age, location, and social and work activities. We describe an approach to use a broad range of social activity data to generate possible heterosexual networks. We start with a large-scale simulation of thousands of people in a city as they go through their daily activities, including work, school, shopping, and activities at home. We extract a social network from these activities where the nodes are the people, and the edges indicate a social interaction, such as working in the same location. This social network captures the correlations between people of different ages, living in different locations, their economic status, and other demographic factors. We use the social contact network to define a bipartite heterosexual network that is embedded within an extended social network. The resulting sexual network captures the biased mixing inherent in the social network, and models based on this pairing of networks can be used to investigate novel intervention strategies based on the social contacts among infected people. We illustrate the approach in a model for the spread of chlamydia in the heterosexual network representing the young sexually active community in New Orleans.

Highlights

  • The structure of heterosexual networks plays an important role in the spread of all sexually transmitted infections (STIs), including chlamydia and gonorrhea

  • We described a new algorithm to generate an ensemble of heterosexual networks based on heterosexual behavior surveys for the young adult African American population in New Orleans

  • The prescribed degree and joint-degree distribution represented the heterosexual network embedded within a social network that captures the biased mixing of the population based on age, physical location, and social activities

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Summary

Introduction

The structure of heterosexual networks plays an important role in the spread of all sexually transmitted infections (STIs), including chlamydia and gonorrhea. These networks are captured in computer simulations by a bipartite graph where the nodes represent the people and the edges are sexual partnerships between nodes of different sexes. The existing algorithms that generate bipartite random graphs preserving degree and joint-degree distributions of the nodes are strictly based on the number of partners people have and not other demographic factors, such as age or location (Newman 2002; Hakimi 1962; Boroojeni et al 2017; Azizi et al 2016, 2017, 2018). In other words, using the extended social network of a person as a source of sexual partner selection when generating a heterosexual network enables the network to capture the bias in heterogeneous mixing based on age, race, economic status, and geographic location (McPherson et al 2001)

Methods
Conclusion

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