Abstract
In 1934, Chavany and Chaignot reported an unusual syndrome that developed in a patient undergoing gold therapy and consisted of continuous vermicular twitching of muscles, like a keyboard motion of the piano being rapidly played, excessive sweating, insomnia, and other mental symptoms. 1 They called it choree fibrillaire de Morvan , after Morvan who apparently had first described this complex of symptoms. 1 This unusual condition has been reported almost exclusively in French medical literature and has been associated primarily with gold therapy and rarely with inorganic mercury intoxication. 2-4 We found no reports of such cases occurring in the United States. REPORT OF A CASE A 30-year-old man with rheumatoid arthritis of recent onset was receiving 50-mg injections of gold sodium thiomalate twice a week. After he had received a total dose of 1,200 mg, he began to experience fatigue, pruritus, sweating, irritability, emotional lability, and insomnia, along with generalized
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