Abstract

Due to the growing public awareness of cardiovascular disease (CVD), blood pressure (BP) estimation models have been developed based on physiological parameters extracted from both electrocardiograms (ECGs) and photoplethysmograms (PPGs). Still, in order to enhance the usability as well as reduce the sensor cost, researchers endeavor to establish a generalized BP estimation model using only PPG signals. In this paper, we propose a deep neural network model capable of extracting 32 features exclusively from PPG signals for BP estimation. The effectiveness and accuracy of our proposed model was evaluated by the root mean square error (RMSE), mean absolute error (MAE), the Association for the Advancement of Medical Instrumentation (AAMI) standard and the British Hypertension Society (BHS) standard. Experimental results showed that the RMSEs in systolic blood pressure (SBP) and diastolic blood pressure (DBP) are 4.643 mmHg and 3.307 mmHg, respectively, across 9000 subjects, with 80.63% of absolute errors among estimated SBP records lower than 5 mmHg and 90.19% of absolute errors among estimated DBP records lower than 5 mmHg. We demonstrated that our proposed model has remarkably high accuracy on the largest BP database found in the literature, which shows its effectiveness compared to some prior works.

Highlights

  • According to a statistical report from the World Health Organization (WHO), cardiovascular disease (CVD) is the leading cause of death worldwide, with an estimated 17.9 million people dying from CVD in 2016, representing 31% of global deaths [1]

  • Blood pressure (BP) is considered to be one of the most important contributory risk factors and, real-time monitoring of blood pressure (BP) plays a crucial role in saving people from premature death caused by CVD

  • Since the raw PPG might contain noise and long sequences, preprocessing is necessary for further feature extraction processes

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Summary

Introduction

According to a statistical report from the World Health Organization (WHO), cardiovascular disease (CVD) is the leading cause of death worldwide, with an estimated 17.9 million people dying from CVD in 2016, representing 31% of global deaths [1]. Blood pressure (BP) is considered to be one of the most important contributory risk factors and, real-time monitoring of BP plays a crucial role in saving people from premature death caused by CVD. They take about one to two minutes to produce one set of diastolic blood pressure (DBP) and systolic blood pressure (SBP) measurements before making another measurement. This type of measurement can be time-consuming and is often inaccurate [2]. (NN),was wasproposed proposedaalong longtime timeago agototomimic mimic the behaviors learning model, called a neural the behaviors of of neurons. generic

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