Abstract

IntroductionHypertrophic cardiomyopathy is the most common type of cardiomyopathy and is characterized by increased heart muscle thickness, that is not explained by abnormal loading conditions. Clinical manifestationsWhile affected patients can be asymptomatic, dyspnoea is the main complaint in those with symptoms. The most severe complication is sudden death, generally due to malignant ventricular arrhythmias. DiagnosisCardiac imaging techniques are the basis for the diagnosis, because they demonstrate the myocardial hypertrophy. TreatmentThe first therapeutic approach consists of negative inotropic agents. Beta-blockers are considered to be the first choice in obstructive forms of this disease. If the combination of these agents and disopyramide does not relieve the symptoms, it might be necessary to resort to invasive procedures in order to reduce the interventricular septum. Implantable defibrillators in selected patients are the key toolsto prevent sudden death.

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