Abstract
AbstractThe sections in this article are:BeginningsEndocrine Nature of the PancreasAction MechanismsLandmarks in Protein Phosphorylation: Mechanism of Action of GlucagonInsulinEarly Development of Ideas About the Mechanism of Action of InsulinInsulin Secretion and BiosynthesisFuels: Consumption and Selection—The Glucose Fatty Acid Cycle and the Role of the PDH ComplexFuel Consumption and SelectionThe Glucose Fatty Acid CycleRole of the Pyruvate Dehydrogenase ComplexPhysiopathological Significance of Pyruvate Dehydrogenase Kinase Regulation in HumansThe Thrifty Phenotype Hypothesis in Relation to Insulin Secretion, Insulin Insensitivity, and the Origins of Non‐Insulin‐Dependent Diabetes MellitusWhere Next?
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