Abstract
The prevalence of coeliac disease in the general population is 0.5–1%; however, most patients remain undiagnosed until adult age. In some cases, the onset is represented by sub-clinical signs, some of which can be found in the mouth. The aim of this research was to identify any associations between the clinical characteristics of coeliac disease and oral manifestations. A structured questionnaire was administered to a group of 237 individuals with coeliac disease. 100% of the subjects fully completed the questionnaire. Among them, 182 (76.7%) were female, 64 patients (27%) were aged 15 to 24 years, 159 (67%) were aged 25 to 55 and 14 (6%) were aged 56 and over. Significant associations were observed in caries prevalence and dentin sensitivity; in addition, an inappropriate diet was related to oral manifestations; following a gluten-free diet could be important to control the gingival bleeding levels and to manage oral symptoms associated to coeliac disease. In general, the presence of inflammatory symptoms in the mouth seems to be associated with general symptoms of inflammation related to coeliac disease.
Highlights
Coeliac disease is an immune-mediated disease, typical of genetically predisposed individuals; it is caused by gluten [1]
The prevalence of coeliac disease in the general population is 0.5–1%; most patients remain undiagnosed until adult age
There are several clinical onsets of the disease, the most common caused by malabsorption [3]; in some cases, the onset is represented by sub-clinical signs, some of which are found in the mouth
Summary
Coeliac disease is an immune-mediated disease, typical of genetically predisposed individuals; it is caused by gluten [1]. There are several clinical onsets of the disease, the most common caused by malabsorption (iron deficiency anemia, hypovitaminosis etc.) [3]; in some cases, the onset is represented by sub-clinical signs, some of which are found in the mouth (herpes-like lesions, recurrent aphthous stomatitis, hypoplasia and dyschromia of the enamel, etc.) [4]. It is characterized by a variety of symptoms, both intestinal and extra-intestinal, including oral manifestations [5].
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
