Abstract
We investigate the fine-grained uncertainty relations for qubit systems by measurements corresponding respectively to two and three spin operators. Then we derive the general bound for a combination of two probabilities of projective measurements in mutually unbiased bases in $d$-dimensional Hilbert space. All of those uncertainty inequalities can be applied to construct different thermodynamic cycles such that the violation of those inequalities will lead to the violation of the second law of thermodynamics. This reveals the relationship between fine-grained uncertainty and the second law of thermodynamics.
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