General and central obesity in adult pre-diabetics: A metabolic derangement to consider

Abstract

Background: Obesity is a well-established risk factor for the development of type 2 diabetes mellitus (T2DM) and its precursor. Aims and Objectives: This study aimed to investigate the comparative overall obesity and central obesity in pre-diabetic and healthy control. Materials and Methods: A cross-sectional study was conducted on 86 pre-diabetics and 86 age and sex-matched control. Fasting blood glucose of <100 was considered normal and 100–125 were considered to be pre-diabetics. General obesity was assessed using total body fat percentage and central obesity as visceral fat as measured by OMRON Body Fat Monitor-Karada Scan. We used a t-test to compare the parameters between two groups of population. Results: A total of 86 pre-diabetes patients and normal patients participated in the study. Total body fat in pre-diabetes was 28.84 ± 6.18 versus normal was 24.87 ± 5.38, P < 0.0001. The visceral fat also showed a higher level in pre-diabetes patients (14.6 ± 1.72 vs. 10.13 ± 2.54, P < 0.0001). Conclusion: General and central obesity are prominent risk factors for metabolic derangements in adult diabetics and pre-diabetics. This study highlights the importance of addressing both forms of obesity in the management and prevention of T2DM and underscores the need for tailored strategies for individuals at different stages of glucose dysregulation.