Abstract

This study aimed to review general anaesthesia protocols for patients undergoing electroconvulsive therapy (ECT) at a tertiary care hospital in Oman, particularly with regards to clinical profile, potential drug interactions and patient outcomes. This retrospective study took place at the Sultan Qaboos University Hospital (SQUH), Muscat, Oman. The electronic medical records of patients undergoing ECT at SQUH between January 2010 and December 2014 were reviewed for demographic characteristics and therapy details. A total of 504 modified ECT sessions were performed on 57 patients during the study period. All of the patients underwent a uniform general anaesthetic regimen consisting of propofol and succinylcholine; however, they received different doses between sessions, as determined by the treating anaesthesiologist. Variations in drug doses between sessions in the same patient could not be attributed to any particular factor. Self-limiting tachycardia and hypertension were periprocedural complications noted among all patients. One patient developed aspiration pneumonitis (1.8%). All patients undergoing ECT received a general anaesthetic regimen including propofol and succinylcholine. However, the interplay of anaesthetic drugs with ECT efficacy could not be established due to a lack of comprehensive data, particularly with respect to seizure duration. In addition, the impact of concurrent antipsychotic therapy on anaesthetic dose and subsequent complications could not be determined.

Highlights

  • Objectives: This study aimed to review general anaesthesia protocols for patients undergoing electroconvulsive therapy (ECT) at a tertiary care hospital in Oman, with regards to clinical profile, potential drug interactions and patient outcomes

  • A total of 504 ECT sessions were performed on 57 patients, including 20 male and 37 female patients

  • A major limitation of the present study was the lack of documentation regarding the energy level, number and duration of the electric shocks delivered during ECT sessions, with regards to the lack of EEG data

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Summary

Introduction

Abstract: Objectives: This study aimed to review general anaesthesia protocols for patients undergoing electroconvulsive therapy (ECT) at a tertiary care hospital in Oman, with regards to clinical profile, potential drug interactions and patient outcomes. All of the patients underwent a uniform general anaesthetic regimen consisting of propofol and succinylcholine; they received different doses between sessions, as determined by the treating anaesthesiologist. Advances in Knowledge - To the best of the authors’ knowledge, this study is the first to evaluate anaesthesia protocols among patients undergoing modified electroconvulsive therapy (ECT) in Oman. Application to Patient Care - Correlating antipsychotic and anaesthetic drug protocols with the quality and duration of ECT-induced seizures may help caregivers choose more suitable pharmaceutical agents. General Anaesthesia Protocols for Patients Undergoing Electroconvulsive Therapy Retrospective analysis of 504 sessions over a five-year period at a tertiary care hospital in Oman. During ECT sessions, anaesthesiologists provide diligent cardiorespiratory monitoring services, life support expertise and the pharmacological reduction of actual seizures while allowing unimpeded electrical activity.[9]

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