General & applied toxicology

Abstract

Volume I General aspects. Part 1 Introductory and basic material: fundamentals of toxicology, B. Ballantyne et al statistics for toxicology, P.N. Lee principles of testing for acute toxic effects, C. Rhodes et al biotransformation of xenobiotics, J. Timbrell toxicokinetics, A.G. Renwick physiologically-based pharmacokinetic modeling, Hon-Wing Leung biochemical mechanisms of toxicology, J. Caldwell alternatives to in vivo studies in toxicology, S.C. Gad acute non-specific toxicity, J.A. Henry and S.L. Cassidy information resources for toxicology, J. Deschamps and Morgan. Part 2 Techniques in toxicity: design of toxicology studies, A. Paine pathological techniques in toxicology, P. Greaves haematology in toxicology studies, D. Woodman and J. Fuller clinical chemistry in toxicology studies, M. Stonard and Evans antidotal studies, N. Bateman and T.C. Marrs quality assurance in toxicology studies, T.R. Stiles hazards in the toxicology laboratory, B. Ballantyne evaluation of toxicity in human subjects, P.N. Bennett. Part 3 Toxicity by routes: parental toxicity, D. Walker peroral toxicity, T.R. Tyler percutaneous toxicity, Hon-Wing Leung inhalation toxicity, P. Hext and I.P. Bennett. Volume II Organ and special toxicity - applied toxicology. Part 1 Target organ toxicity: neurotoxicity, J.N. LeFauconnier peripheral sensory irritation, B. Ballantyne nephrotoxicity, B.A. Lock systemic pulmonary toxicity, J.P. Kehrer pulmonary hypersensitivity reactions, H.C. Lewinsohn and H.D. Burleigh-Flayer ophthalmic toxicology, B. Ballantyne cardiovascular toxicity, S.I. Baskin heptotoxicity, P. Grasso and R.H. Hinton toxicity of the pancreas, J.M. Braganza toxicology of skeletal muscle, K.E. Misulis et al toxicology of bone, A.G.B. Lansdowne cutaneous toxicity, S.J. Hermansky ototoxicity, Forge and E.S. Harper, toxicology of the adrenal, thyroid and endocrine pancreas, J.A. Thomas immunotoxicology, K. Miller and C. Neredith haematotoxicology, J. Amess. Part 2 Special toxicology: mutagenicity, A. Tweats cytogenetics, D. Anderson chemical carcinogenesis (genotoxic), D.B. McGregor chemical carcinogenesis (epigenetic), C. Berry Reproductive toxicology, J.N. Ratcliffe and F. Sullivan developmental toxicology, R.W. Tyl neonatal toxicology, S. Kacew. Part 3 Regulatory tocicology: overview of regulatory agencies, G. Diggle regulation of drugs in Europe and the United Kingdom, R.D. Mann regulation of drugs on the North American continent, M.B. Vernoy regulation of veterinary product in Europe and the United Kingdom, K. Woodward regulation of veterinary products in the United States, K. Woodward regulation of industrial chemicals and pesticides in Europe and the United Kingdom, R. Fielder and Martin regulation of food additives and food contact materials on the North American continent, M.B. Vernoy. Part 4 Toxicology in special situations: pharmaceutical toxicology, P.F. D'Arcy medical devices, Adams. Part contents.