Abstract
The decade between this Symposium and the previous one (Cold Spring Harbor Symposium on Quantitative Biology, 1941) concerned with “the gene” encompasses the period in which biochemical genetic investigations of Neurospora have flourished. It is therefore fitting that consideration should be given to the contribution of Neurospora investigations to our knowledge of the gene and its action. I shall not attempt a general review of all the work dealing with the biochemistry and genetics of Neurospora since it has been frequently reviewed during the past few years (Beadle, 1945; Bonner, 1950; Tatum, 1949; Horowitz, 1950; Mitchell, 1950). To furnish a background, however, for the material which I shall review, I shall summarize briefly the paper I presented five years ago before the Cold Spring Harbor Symposium on Heredity and Variation in Microorganisms (Bonner, 1946). I shall also present our recent work within the framework of the conclusions reached...
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