Abstract
Allergic disease results from the interplay between individual genetic susceptibility and environmental exposures. 1 The genetic contribution to allergic disease has been estimated from twin studies to be generally greater than 50%, with heritability estimates ranging from 36% to 79%. 2 The environmental contribution to allergic disease is evidenced by the increase in the prevalence of allergy in the past decades. This increase is the result of changes in the environment. Interestingly, children raised on farms appear to have been protected against this increase in prevalence compared with children not raised on farms. Protective lifestyle factors on the farm include exposure to livestock, the consumption of unpasteurized farm milk, and increased endotoxin levels in the farm environment. 3 The
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
