Abstract

The advances in recombinant DNA technology which have occurred in the past two decades have led to the increasing use of genetically engineered micro-organisms (GEMs) in the production of a variety of therapeutic and industrially important products such as human insulin, interferons and growth hormones.1 Other examples which involve use of GEMs in practical applications include the development of recombinant vaccines,2 of ice– bacteria to reduce frost damage to crops3 and microbial and virus insecticides.4,5 The use of genetically engineered bacteria constructed to degrade specific recalcitrant pollutants has also been suggested.6,7

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