Abstract
Michele De Luca at the University of Modena and Reggio Emilia in Italy has used gene therapy to help a boy with the condition who was close to death. He and his team took a 4-centimetre-square patch of remaining skin and genetically altered the cells in a dish, correcting the mutation. They then grew the cells into sheets of skin, which were grafted onto the boy's body, covering around 80 per cent of him. Marcel Jonkman of University Medical Center Groningen in the Netherlands says the biggest fear with this kind of gene therapy is that it might trigger cancer in the future.
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