Abstract
Papaya (Carica papaya) is severely damaged by the papaya ringspot virus (PRSV). This review focuses on the development of PRSV resistant transgenic papaya through gene technology. The genetic diversity of PRSV depends upon geographical distribution and the influence of PRSV disease management on a sequence of PRSV isolates. The concept of pathogen-derived resistance has been employed for the development of transgenic papaya, using a coat protein-mediated, RNA-silencing mechanism and replicase gene-mediated transformation for effective PRSV disease management. The development of PRSV-resistant papaya via post-transcriptional gene silencing is a promising technology for PRSV disease management. PRSV-resistant transgenic papaya is environmentally safe and has no harmful effects on human health. Recent studies have revealed that the success of adoption of transgenic papaya depends upon the application, it being a commercially viable product, bio-safety regulatory issues, trade regulations, and the wider social acceptance of the technology. This review discusses the genome and the genetic diversity of PRSV, host range determinants, molecular diagnosis, disease management strategies, the development of transgenic papaya, environmental issues, issues in the adoption of transgenic papaya, and future directions for research.
Highlights
Papaya (Carica papaya L) belongs to the family Caricaceaeand is one of the most economically important fruit crops in many tropical and subtropical countries
Transgenic papaya via gene technology has been used for papaya ringspot virus (PRSV) disease management
We find that PRSV-resistant papaya varieties have been developed using coat protein (CP) genes or RNA interference
Summary
Papaya (Carica papaya L) belongs to the family Caricaceaeand is one of the most economically important fruit crops in many tropical and subtropical countries. PRSV has been recognized as a destructive disease in many tropical and subtropical areas including the USA, South America, Africa [9], India [10], Thailand, Taiwan, China and the Philippines [11], Mexico [12], Australia [13], Japan [14], French Polynesia, and the Cook islands [15] resulting in the decline in fruit production This disease can cause up to 100% losses of crops in some regions [16]. SunUp and Rainbow have been widely grown in USA without any adverse effects on human health [25] In countries such as Australia, Jamaica, Venezuela, Vietnam, Thailand, Taiwan, and Philippines, the CP gene from their geographic region has been used to develop region-specific transgenic Papaya for the control of PRSV [20]. The PRSV-W type affects cucurbits but not papaya while the PRSV-P type affects papaya and cucurbits
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
