Abstract
Three main theories of autotetraploid segregation have been propounded, the Muller hypothesis based on the random assortment of chromosomes at meiosis, the Haldane hypothesis based on the random assortment of chromatids, and the Mather hypothesis in which the ratios are considered to be not fixed but varying according to the amount of quadrivalent formation and the distance of a gene from the centromere. The first two hypotheses are special cases of the last, which is, in general, the most satisfactory for explaining observed data.
Published Version
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