Abstract
The cell wall (CW) as a first line of defense against biotic and abiotic stresses is of primary importance in plant biology. The proteins associated with cell walls play a significant role in determining a plant's sustainability to adverse environmental conditions. In this work, the genes encoding cell wall proteins (CWPs) in Arabidopsis were identified and functionally classified using geneMANIA and GENEVESTIGATOR with published microarrays data. This yielded 1605 genes, out of which 58 genes encoded proline-rich proteins (PRPs) and glycine-rich proteins (GRPs). Here, we have focused on the cellular compartmentalization, biological processes, and molecular functioning of proline-rich CWPs along with their expression at different plant developmental stages. The mined genes were categorized into five classes on the basis of the type of PRPs encoded in the cell wall of Arabidopsis thaliana. We review the domain structure and function of each class of protein, many with respect to the developmental stages of the plant. We have then used networks, hierarchical clustering and correlations to analyze co-expression, co-localization, genetic, and physical interactions and shared protein domains of these PRPs. This has given us further insight into these functionally important CWPs and identified a number of potentially new cell-wall related proteins in A. thaliana.
Highlights
Reviewed by: Dapeng Wang, University of Oxford, UK Sergio J
We have focused on the cellular compartmentalization, biological processes, and molecular functioning of proline-rich cell wall proteins (CWPs) along with their expression at different plant developmental stages
The mined genes were categorized into five classes on the basis of the type of proline-rich proteins (PRPs) encoded in the cell wall of Arabidopsis thaliana
Summary
The cell wall (CW), considered as first line of defense in plants, is composed of polysaccharides (cellulose, hemicellulose, pectin), and proteins. Encoding of a large number of proteins in same genome and simultaneous expression of the genes in the same tissue of plant are the different grounds that had created difficulty for us to perceive the exact biology of the EXTs. The O-glycoproteins possessing EXT domains were integrated in the CW, put together by the different post translational modifications (PTMs), comprising processing of signal peptide by endoplasmic reticulum, proline hydroxylation, O-glycosylation, and Tyr cross linking in the CW (Nguema-Ona et al, 2014). This implicate structural roles of GRPs in conferring defense mechanisms
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