Abstract

Gene function in schistosomes: recent advances toward a cure

Highlights

  • Specialty section: This article was submitted to Evolutionary and Genomic Microbiology, a section of the journal Frontiers in Genetics

  • Despite considerable efforts and highly uneven temporal and regional improvements since that point (Chen and Ravallion, 2008; United Nations, 2013), each one of these impoverished persons is potentially exposed to infectious diseases due to precarious conditions, such as contaminated drinking water, malnutrition, lack of sanitation or shelter, and inadequate basic services including education, health and security (WHO-World Health Organization, 2012; United Nations, 2013)

  • Whereas helminth infections are estimated to affect more than one billion people in sub-Saharan Africa, Asia and the Americas (Hotez et al, 2007), the global expenditures on helminth infection targeted research and development (R&D) was a mere US$66.8 million in 2008, with uneven distribution across diverse diseases and focus mainly for basic research (Institute of Medicine, 2011)

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Summary

Introduction

Specialty section: This article was submitted to Evolutionary and Genomic Microbiology, a section of the journal Frontiers in Genetics. Whereas helminth infections are estimated to affect more than one billion people in sub-Saharan Africa, Asia and the Americas (Hotez et al, 2007), the global expenditures on helminth infection targeted research and development (R&D) was a mere US$66.8 million in 2008, with uneven distribution across diverse diseases and focus mainly for basic research (Institute of Medicine, 2011).

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Conclusion

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