Abstract
This study was conducted during 2017-19 with the objective to provide data of distribution of blood group of ABO and Rh(D) and gene frequency among the population of three districts; Multan, Lodhran and Khanewal (Multan Division), Pakistan. This information will provide basic facts and figures of region to geneticists, practitioners and blood transfusion programmers. From both genders total 440 subjects were selected from schools and colleges students, prisoners and factory workers etc. randomly in different regions of three districts. Blood samples of both genders were tested for blood groups ABO and Rh(D) factor with help of open slide test method. To observe agglutination, a drop of the antisera, anti-A, anti-B and anti-D were mixed with every blood sample and shook gently for 60 seconds. The predominant blood group was O with 36.48%, 42.57% and 42.08% presence in Multan, Lodhran and Khanewal respectively in all the Rh(D) positive subjects. In Rh(D) negative subjects, blood group A was found predominant with 5.40% in Multan district only amongst the three districts. In Multan the percentage of Rh(D) Positive was 90.55% and Rh(D) negative was 9.45%. In Lodhran, the percentage of Rh(D) positive was 93.25% and Rh(D) negative was 6.75%. in Khanewal, the percentage of Rh(D) positive was 91.22% and Rh(D) negative was 8.78%. Among the 3 districts studied, both Rh(D) positive and Rh(D) negative frequency of blood groups was O> A> B> AB> except Multan where blood group “A” was common among Rh(D) negative subjects. Keywords: ABO; Distribution; District; Division; Frequency; Population; Rh(D) http://dx.doi.org/10.19045/bspab.2021.100124
Highlights
This study was conducted during 2017-19 with the objective to provide data of distribution of blood group of ABO and Rh(D) and gene frequency among the population of three districts; Multan, Lodhran and Khanewal (Multan Division), Pakistan
O blood group which is with Rh type of positive is known to be dominant in Khanewal district population
Based on Rhesus (Rh) factor, the present study confirmed that Rh(D)+ has high rate frequency % than Rh(D)- frequency percentage in Multan Division (3 studied districts) which was observed in past studies on different types of ethnic groups [14, 23, 24]
Summary
This study was conducted during 2017-19 with the objective to provide data of distribution of blood group of ABO and Rh(D) and gene frequency among the population of three districts; Multan, Lodhran and Khanewal (Multan Division), Pakistan. This information will provide basic facts and figures of region to geneticists, practitioners and blood transfusion programmers. From both genders total 440 subjects were selected from schools and colleges students, prisoners and factory workers etc. The frequencies expressed as in different percentages were calculated, Chi-square test for the distribution of blood group and Rh antigen were carried under the valuable assumption of Hardy-Weinberg equilibrium
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