Abstract
Three forms of supernatant malate dehydrogenase occur in most salmon and trout. Dissociation and recombination experiments on the purified forms show that these three isoenzymes arise from the association of two types of subunits (A and B) into dimers. The A and B subunits are shown to be under the control of separate genes. The detection of duplicate genes for supernatant malate dehydrogenase provides additional support for the hypothesis that salmonid fishes are tetraploid.
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