Abstract

The uropathogenic Escherichia coli strain J96 (04:K6) is able to produce four adherence factors [P-fimbriae ( pap and prs), F1C-fimbriae ( foc) and Type 1-fimbriae ( fim)], two α-hemolysins ( hfyI and II) and the cytotoxic necrotizing factor type 1 ( cnf1). Using phenotypic test systems and genotypic analysis, it has been shown that the mutant strain J96-M1 has lost the hlyII, prs and cnf1 genes. The three virulence associated determinants are linked on one particular region on the chromosome, which is termed ‘pathogenicity island II’ (Pai II).

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