Gender Variation in Ocular Biometry and Ultrasound Biomicroscopy of Primary Angle Closure Suspects and Normal Eyes

Abstract

To compare A-scan biometry and ultrasound biomicroscopy of primary angle closure suspects (PACS) with age-matched normal Indian eyes. Subjects with primary angle closure suspects (n=57 eyes) and normal eyes (n=57 eyes) underwent A-scan biometry and ultrasound biomicroscopy. Anterior chamber depth (ACD), anterior chamber angle (ACA), axial length (AXL), lens thickness, relative lens position (RLP), central corneal thickness (CCT), angle opening distance 500, trabecular-ciliary process distance (TCPD), iris-ciliary process distance, iris thickness, and scleral-ciliary process angle were measured. The subjects were divided into males, females, and combined groups for analysis. The parameters were compared using independent sample t test with Bonferroni correction for multiple comparisons. In the combined group, the PACS subjects presented a significantly low ACD, AXL, CCT, AOD500, TCPD, ACA (P<0.001), and RLP (P=0.04). In males, RLP was anterior (P=0.002) and in females, the lens thickness (P<0.001) was significantly thicker among the PACS group. ACD, AXL, CCT, TCPD, ACA, and angle opening distance 500 of the PACS group were significantly lower than in normals. In females, the lens in PACS was thicker than in normals. Lens in males was more anterior-placed in PACS group than in normals.