Abstract

Purpose: Increasing clinical evidence suggests an overrepresentation of gender variance (GV) among patients with autism spectrum disorders (ASDs). This retrospective chart review aims to contribute to the existing literature on co-occurring ASD and gender dysphoria (GD). We compare the rate of parent-reported GV in patients with an ASD diagnosis to that of parent-reported GV in a normative nonreferred data set.Methods: Child Behavior Checklist (CBCL) charts were collected from 492 children and adolescents (409 natal males and 83 natal females) aged 6–18 years who have received a diagnosis of ASD at the New York University Child Study Center. Parent-reported GV was determined through endorsement of CBCL sex item 110, which assesses the presence of gender-related issues. We calculated the odds ratio of endorsement of item 110 between our ASD sample and the CBCL sample data.Results: The subjects diagnosed with ASD were 7.76 times more likely to report GV than the CBCL sample. This finding was statistically significant. About 5.1% of the patients in the ASD group and 0.7% of the CBCL nonreferred group endorsed sex item 110. 5.1% of natal males and 4.8% of natal females endorsed sex item 110. Neither gender nor age influenced the rate of endorsement.Conclusion: This finding supports the growing research suggesting a heightened co-occurrence rate of ASD and GD. Focus should be placed upon improving our understanding of the nature of this co-occurrence and on gender identity development within the atypical development of ASD.

Highlights

  • Autism spectrum disorders (ASDs) are a set of neurodevelopmental disorders that are characterized by impairments in social communication skills and repetitive and restricted interests and behaviors.[1]

  • Child Behavior Checklist (CBCL) were collected from all patients who were between ages 6 and 18 years and had received formal diagnoses of ASDs (i.e., ASD, Asperger’s syndrome, pervasive developmental disorders, and all associated not otherwise specified [NOS] diagnoses) between January 2011 and January 2015 at the New York University (NYU) Child Study Center in midtown Manhattan, New York City

  • Odds ratio was calculated between our ASD group and the nonreferred sample from CBCL nonreferred normative data

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Summary

Introduction

Autism spectrum disorders (ASDs) are a set of neurodevelopmental disorders that are characterized by impairments in social communication skills and repetitive and restricted interests and behaviors.[1]. GD is a DSM-5 diagnosis characterized by distress caused by a persistent incongruence between one’s natal sex and expressed gender,[1] and GV is a broader term that describes any numbers of variability between assigned sex and experienced/expressed gender. An increasing number of researchers and practitioners have noticed a high rate of co-occurrence between GD and/ or GV and ASDs. Many case studies have suggested an overrepresentation of GD among clients with ASDs and vice versa.[5,6,7,8] De Vries et al.[4] systematically measured this overrepresentation in a large-scale Dutch-based a Aron Janssen et al 2016; Published by Mary Ann Liebert, Inc. Many case studies have suggested an overrepresentation of GD among clients with ASDs and vice versa.[5,6,7,8] De Vries et al.[4] systematically measured this overrepresentation in a large-scale Dutch-based a Aron Janssen et al 2016; Published by Mary Ann Liebert, Inc

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