Gender effect on coronary angiographic findings in evaluation of chest pain

Abstract

Objective: The primary objective of this study is to evaluate the effect of gender on angiographic findings in referred patients with chest pain and to study the gender-related differences in risk factors in patients with coronary artery disease as a secondary goal. Design: A retrospective, clinical study of 230 patients with chest pain. Setting: Mosul Heart Center – Ibn Sina Teaching Hospital. Patients and methods: From Sept. 1st 2011 to Jan. 31st 2012, a total of 230 (100 female, 130 male) patients with chest pain who underwent diagnostic coronary angiography in Mosul Heart Center – Ibn Sina Teaching Hospital were studied retrospectively. Both the whole female population and post-menopausal females as a separate group was compared with a whole male population depending on the presence or absence of coronary artery disease identified by coronary angiography. The main outcome of cardiovascular risk factors: hypertension, diabetes mellitus, hypercholesterolemia, smoking and family history of coronary heart disease were also studied in relation to the gender. Results: The correlation between the whole female and male populations with positive coronary angiography: 59% (59/100) vs. 89.2% (116/130) respectively, was statistically significant (p< 0.001). The correlation between post-menopausal women and whole male population with positive coronary angiography: 67.14% (47/70) vs. 89.2% (116/130) was also statistically significant (p< 0.05). The mean age (yr) ± SD of whole female population with positive coronary angiography was (57.48± 8.8), while it was (53.34± 9.0) for male population with positive coronary angiographic findings. The correlation was statistically significant (p