Abstract
Objective — to compare the gender-associated effects of 6-month (М6) treatment of patients aged 0.05), except for a decrease in LVMI in men compared to 9.5 % for CCB (p 0.05).Conclusions. Treatment of patients with 1—2 degrees of AH during 6 months with ACE inhibitors/ARB ± indapamide or CCB ± indapamide, both men and women, resulted in the significant decrease in brachial and central blood pressure. However, regardless of the type of treatment, women achieved lower levels of brachial blood pressure than men. CCB-based therapy, compared to ACE inhibitors/ARB therapy, contributed to more pronounced decreased in central blood pressure in women, decreased the AP both men and women, AIx75 in women. In addition, 6-months antihypertensive therapy using CCB ± indapamide was reduce LVMI on 9.3 %, but only in men, which was not accompanied by changes in diastolic function, regardless of the type of treatment and gender.
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