Gender Differences in Coronary Profiles of Chronic Coronary Syndrome Patients

Abstract

Background: Chronic coronary syndrome (CCS) is a recently defined entity that necessitates evaluating individual clinical risk factors in this cohort. Objective: The objective of the present study was to evaluate patients with CCS and examine their coronary profiles in order to delineate differences between genders. Methods: A cross-sectional analysis was conducted on 51 patients who met the criteria of CCS and have undergone both coronary angiography and CT coronary angiography. Analyses were conducted using univariate statistics. Results: The cohort consisted of mainly Kuwaiti nationals with an average age of 61 ± 10 years. Females consisted 41% of the cohort, were older by an average of 9 years (P = 0.001), and were overweight (67% vs. 44%). Males were more likely to be cigarette consumers (47% vs. 14%; P = 0.022). Females had more comorbidities such as hypertension (86% vs. 80%) and atrial fibrillation (24% vs. 10%), excluding stroke (0% vs. 3.3%), and coronary artery disease (71% vs. 83%). Males had an elevated level of creatinine (88 vs. 72 umol/L; P = 0.045). Other results were not significantly different between genders. Males were more likely to be prescribed aspirin upon admission (100% vs. 81%; P = 0.026), however, this difference decreased upon discharge (97% vs. 86%; P = 0.297). Recurrent ischemia (12%; n = 6) was the most common major outcome recorded. Conclusions: This study shows that females were more likely to be older than their male counterparts whereas males were more often on aspirin and more likely to be cigarette smokers. We found no significant differences in comorbidities, admission laboratory and imaging results, nor outcomes between genders.