Gender differences and outcome of melanoma patients

Francesca Morgese,Mariangela Torniai,Rossana Berardi,Giulia Marcantognini,Alessandro Bittoni,Caterina Sampaolesi,Giuseppe Ricotti,Alfredo Giacchetti,Stefano Cascinu,Stefano Serresi,Azzurra Onofri,Alberta Pilone

doi:10.1186/1479-5876-13-s1-p13

Abstract

Background In the United States, 80,000 cases of melanoma are expected in 2014, representing 5% and 4% of all diagnosis of cancer in men and women, respectively. In Italy in 2013, there were an estimated 10,500 cases of cutaneous melanoma, with an incidence of 14.3 cases per 100,000 male population and 13.6 cases per 100,000 female population. Female melanoma patients generally exhibit significantly longer survival than male patients. The aim of this study is to evaluate the role of gender in survival of melanoma patients and the relationship between gender and pathologic features of the neoplasm.

Highlights

In the United States, 80,000 cases of melanoma are expected in 2014, representing 5% and 4% of all diagnosis of cancer in men and women, respectively.In Italy in 2013, there were an estimated 10,500 cases of cutaneous melanoma, with an incidence of 14.3 cases per 100,000 male population and 13.6 cases per 100,000 female population.Female melanoma patients generally exhibit significantly longer survival than male patients.The aim of this study is to evaluate the role of gender in survival of melanoma patients and the relationship between gender and pathologic features of the neoplasm
Materials and methods In this retrospective study, we examined 1,023 consecutive patients treated at the Department of Medical Oncology and at the Department INRCA-IRCCS of Dermatology in Ancona, Italy from February 1987 to March 2014
Subgroups analysis showed that women had a significant advantage in 12-year disease free survival (DFS) and 12-year overall survival (OS) adjusted for Breslow thickness (T1-T2 melanomas, p

Summary

Introduction

In the United States, 80,000 cases of melanoma are expected in 2014, representing 5% and 4% of all diagnosis of cancer in men and women, respectively.In Italy in 2013, there were an estimated 10,500 cases of cutaneous melanoma, with an incidence of 14.3 cases per 100,000 male population and 13.6 cases per 100,000 female population.Female melanoma patients generally exhibit significantly longer survival than male patients.The aim of this study is to evaluate the role of gender in survival of melanoma patients and the relationship between gender and pathologic features of the neoplasm. In the United States, 80,000 cases of melanoma are expected in 2014, representing 5% and 4% of all diagnosis of cancer in men and women, respectively. In Italy in 2013, there were an estimated 10,500 cases of cutaneous melanoma, with an incidence of 14.3 cases per 100,000 male population and 13.6 cases per 100,000 female population. Female melanoma patients generally exhibit significantly longer survival than male patients. The aim of this study is to evaluate the role of gender in survival of melanoma patients and the relationship between gender and pathologic features of the neoplasm

Objectives

Methods

Results