Abstract
BackgroundPercutaneous coronary intervention (PCI) of total chronic coronary occlusion (CTO) still remains a major challenge. Insignificant data are reported in the literature about gender differences in CTO-PCI in the era of new drug-eluting stents. In this study we analysed the impact of gender on procedural characteristics, complications and acute results.MethodsBetween 2010–2015 we included 780 consecutive patients. They underwent PCI for at least one CTO. Antegrade and retrograde CTO techniques were applied.ResultsPatients undergoing CTO-PCI were mainly men (84%). Male patients were younger (66.9 years ±10.6 vs. 61.1 years ±10.4; p < 0.001), more often smokers, but less frequently had a history of coronary artery disease (24.4% vs. 32.7%; p = 0.085) compared with female patients. Female patients more often had diabetes mellitus (29.6% vs. 26.7%; p = 0.55) and hypertension (82.7% vs. 80.7%; p = 0.55). There were no differences with respect to the amount of contrast fluid, fluoroscopy time and examination time as well as to the length of the stent or the number of the stents. The stent diameter was slightly smaller in women, which was not surprising because the lumen calibre tends to be smaller in women than in men (3.0 mm (2.5–3) vs. 3.0 mm (3–3.5); p < 0.001). The success rates were 81.0% in women and 80.1% in men. There was no significant interaction between gender and procedural success and complication rates.ConclusionsOur retrospective study suggests that women and men have a comparable success rate at a low complication rate after recanalisation of CTO.
Highlights
Recanalisation of total chronic coronary occlusion (CTO) still remains a major challenge in interventional cardiology
Percutaneous coronary intervention (PCI) of CTO is a beneficial tool in coronary artery intervention; if significant myocardial ischaemia is present and there are clinical symptoms due to ischaemia, recanalisation is clearly indicated
The left ventricular function can be improved, more invasive therapies such as coronary artery bypass graft (CABG) surgery can be avoided at lower complication rates and even the prognosis of the disease can be improved in
Summary
Recanalisation of total chronic coronary occlusion (CTO) still remains a major challenge in interventional cardiology. The prevalence of CTO has been reported to be up to 30% among patients with a clinical indication for coronary angiography [2]. Percutaneous coronary intervention (PCI) of CTO is a beneficial tool in coronary artery intervention; if significant myocardial ischaemia is present and there are clinical symptoms due to ischaemia, recanalisation is clearly indicated. Percutaneous coronary intervention (PCI) of total chronic coronary occlusion (CTO) still remains a major challenge. Insignificant data are reported in the literature about gender differences in CTO-PCI in the era of new drug-eluting stents. Methods Between 2010–2015 we included 780 consecutive patients They underwent PCI for at least one CTO.
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