Abstract
BackgroundThe goal of the present study was to assess the effects of computed tomography (CT)-guided iodine-125 (125I) seed implantation or gelatin sponge particle (GSP) embolization on patients with giant benign sacral neurogenic tumors.MethodsA total of 24 cases with giant sacral neurogenic tumor were performed in a retrospective study between 2000 and 2012. Nineteen cases received surgical resection, and five cases received non-surgical treatment. In surgical group, patients with type III sacral tumor had received a combined anterior-posterior approach and patients with type IV were treated with simple anterior approach. In non-surgical group, CT-guided 125I seed implantation or GSP embolization was applied to occlude vessels. Besides, CT scanning or magnetic resonance imaging was used to assess the size and development of tumors.ResultsTwo of the five patients were treated three times with GSP embolization, one had received GSP embolization combined with CT-guided 125I seed implantation, one case did not receive any treatment, and one patient was lost to follow-up. Patients in non-surgical group were followed up for 2–8 years.ConclusionsOur study suggested that CT-guided 125I seed implantation or GSP embolization treatment is very useful to slow down the development of giant benign sacral neurogenic tumors.
Highlights
The goal of the present study was to assess the effects of computed tomography (CT)-guided iodine-125 (125I) seed implantation or gelatin sponge particle (GSP) embolization on patients with giant benign sacral neurogenic tumors
Eighteen cases underwent marginal resection of distal S2 never root and kept the unilateral S1 nerve root as horizontal as possible. Another case underwent partial sacral resection (PSR) because of a wide range of S1 invaded by tumors
Our results showed that there was a slow development of tumors for patients who received gelfoam embolization or gelfoam embolization combined with CT-guided 125I seed implantation and none of patients suffered a local relapse
Summary
The goal of the present study was to assess the effects of computed tomography (CT)-guided iodine-125 (125I) seed implantation or gelatin sponge particle (GSP) embolization on patients with giant benign sacral neurogenic tumors. The complete resection of the tumor is considered to be an appropriate choice for a patient with sacral neurogenic. Conservative treatments such as interventional perfusion [4], radiofrequency ablation [5], endovascular embolization techniques, and computed tomography (CT)-guided Iodine-125 (125I) seed implantation are alternative approaches for neurogenic tumors. Embolization provides an effective treatment for sacral neurogenic tumors by blocking the tumor blood supply and promoting. CT-guided 125I seed implantation is applied in the treatment of lung cancer [9], prostate cancer [10], spinal metastasis, and primary paraspinal malignancies [11]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
