Abstract
• Gelatin stabilized silver nanoparticles were developed. • Lactose crosslinked gelatin-silver nanocomposite (LGAg) hydrogels are prepared by Schiff base bonding. • The LGAg hydrogels showed good antibacterial activity against E. coli and S. aureus. • LGAg nanocomposite hydrogels have potential use as wound dressings. A simple one-step method was used to prepare lactose crosslinked gelatin-silver nanocomposite (LGAg) hydrogels by Schiff base bonding for wound dressing applications. The developed LGAg nanocomposite hydrogels were characterized by FTIR, XRD, UV-spectroscopy, and SEM to confirm hydrogel structure, morphology, and silver nanoparticle formation, and displayed potent antibacterial activities against Escherichia coli and staphylococcus aureus . Our results show the hydrogel nanocomposites produced have potential applications as wound dressing materials.
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