Gelatin Matrix as Functional Biomaterial for Immobilization of Nanoparticles of Metal-Containing Compounds.

Abstract

The data concerning the synthesis and physicochemical characteristics of specific functional biomaterials-biopolymer-immobilized matrix systems based on gelatin as an array and chemical compounds, which include atoms of various metal elements-are systematized and discussed. The features of this biopolymer which determine the specific properties of the immobilized matrix systems formed by it and their reactivity, are noted. Data on gelatin-immobilized systems in which immobilized substances are elemental metals and coordination compounds formed as a result of redox processes, nucleophilic/electrophilic substitution reactions, and self-assembly (template synthesis), are presented. The possibilities of the practical use of metal-containing gelatin-immobilized systems are promising for the future; in particular, their potential in medicine and pharmacology as a vehicle for "targeted" drug delivery to various internal organs/tissues of the body, and, also, as potential biosensors is noted.