Geert‐Jan Boons

Abstract

Angewandte Chemie International EditionVolume 55, Issue 14 p. 4392-4392 Author ProfileFree Access Geert-Jan Boons First published: 23 November 2015 https://doi.org/10.1002/anie.201510191AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract “My favorite author (fiction) is Louis Paul Boon. The downside of my job is spending too much time away from home ...” This and more about Geert-Jan Boons can be found on page 4392. 1 Table 1. Geert-Jan Boons Date of birth: April 7, 1962 Position: UGA Foundation Distinguished Professor in Biochemical Sciences, Department of Chemistry and the Complex Carbohydrate Research Center, University of Georgia; Professor and Chair of the Department of Medicinal and Biological Chemistry, Utrecht University E-mail: gjboons@ccrc.uga.edu Homepage: http://cell.ccrc.uga.edu/∼gjboons/boons/Home.htm Education: 1997 MSc, Leiden University 1991 PhD supervised by Prof. Dr. J. H. van Boom, Leiden University 1991–1993 Ramsay Memorial Fellow with Prof. Dr. S. V. Ley, Imperial College, London, and University of Cambridge Awards: 2003 Carbohydrate Research Award for Creativity in Carbohydrate Chemistry, International Carbohydrate Association (ICO); 2004 Horace Isbell Award, American Chemical Society (ACS); 2014 Roy L. Whistler International Award in Carbohydrate Chemistry, ICO; 2015 Hudson Award, ACS; 2016 Arthur C. Cope Scholar Award, ACS Current research Glycoscience, synthetic vaccine and immune modulators, bioorthogonal chemistry, molecular recognition Hobbies: Cooking, reading, dog training, bee keeping My favorite author (fiction) is Louis Paul Boon. The downside of my job is spending too much time away from home. My favorite motto is “with a little bit of luck”. The biggest problem that scientists face is administrators. If I won the lottery, I would give it all away. When I'm frustrated, I go for a walk with my dogs. My favorite place on earth is home. If I were not a scientist, I would be a chef. My most exciting discovery to date has been to break immune tolerance against tumor-associated carbohydrate antigens with a fully synthetic vaccine. My greatest achievement has been training students who eventually will start their own independent career. My 5 top papers: References 1“Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions”: X. Ning, J. Guo, M. A. Wolfert, G. J. Boons, Angew. Chem. Int. Ed. 2008, 47, 2253; Wiley Online LibraryCASPubMedWeb of Science®Google ScholarAngew. Chem. 2008, 120, 2285. (A reagent that reacts exceptionally fast with azido-containing biomolecules.) Wiley Online LibraryGoogle Scholar 2“Modular Synthesis of Heparan Sulfate Oligosaccharides for Structure–Activity Relationship Studies”: S. Arungundram, K. Al-Mafraji, J. Asong, F. E. Leach III, I. J. Amster, A. Venot, J. E. Turnbull, G. J. Boons, J. Am. Chem. Soc. 2009, 131, 17394. (Allows the preparation of well-defined heparan sulfate oligosaccharide libraries.) CrossrefCASPubMedWeb of Science®Google Scholar 3“Chiral auxiliary mediated 1,2-cis-glycosylations for the solid supported synthesis of a biologically important branched α-glucan”: T. J. Boltje, J.-H. Kim, J. Park, G. J. Boons, Nat. Chem. 2010, 2, 552. (A combination of classical and auxiliary-mediated neighboring-group participation for controlling anomeric selectivities.) CrossrefCASPubMedWeb of Science®Google Scholar 4“Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine”: V. Lakshminarayanan, P. Thompson, M. A. Wolfert, T. Buskas, J. M. Bradley, L. B. Pathangey, C. S. Madsen, P. A. Cohen, S. J. Gendler, G. J. Boons, Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 261. (The vaccine was efficacious in reversing tolerance and generating a therapeutic response in a mouse model for breast cancer.) CrossrefCASPubMedWeb of Science®Google Scholar 5“A General Strategy for the Chemoenzymatic Synthesis of Asymmetrically Branched N-Glycans”: Z. Wang, Z. S. Chinoy, S. G. Ambre, W. Peng, R. McBride, R. P. de Vries, J. Glushka, J. C. Paulson, G. J. Boons, Science 2013, 341, 379. (The preparation of full cellular glycomes to investigate the specificities and biology of glycan-binding proteins.) CrossrefCASPubMedWeb of Science®Google Scholar Volume55, Issue14March 24, 2016Pages 4392-4392 ReferencesRelatedInformation