Gebeliğin İlk Trimesterindeki Anemi Etyolojisinde Mikrobesin Eksikliğinin Önemi

Abstract

Objective: To determine the frequency of anemia in pregnant women admitted to our hospital for the purpose of examination in the first trimester, to determine the location of micronutrient defi- ciencies in the etiology of anemia and to make analysis of demo- graphic factors associated with anemia. Methods: This study included 366 pregnant women below 12 weeks of gestation between November 2011 and February 2013. Pregnant women together with demographic data were examined in terms of hemoglobin, hematocrit, serum iron, total iron bind- ing capacity, ferritin, folate, vitamin B12 levels. Tests were statis- tically evaluated with demographic analysis. Results: The mean maternal hemoglobin, hematocrit, serum iron, total iron binding capacity, ferritin, folate, and vitamin B12 levels were respectively 12.6±1.02 g/dl, 36%±4.12, 76.63±44.76 μg/dl, 302.28±93.14 ng/dl, 19.35±20.43 ng/ml, 11.2±8.31 ng/ml and 187.2±101.14 pg/ml. The study evaluated 344 pregnant women and anemia was detected in 79 of them. In our study, the frequency of anemia was calculated to be 22.96%. Analyzing the etiology of anemic pregnant women, iron deficiency anemia was diagnosed in 35 patients (44.3%), vitamin B12 deficiency in 44 patients (55.7%), combination of vitamin B12 and iron deficiency was found in 9 patients. None of the patients were found to have folic acid deficiency. Conclusion: The frequency of anemia in pregnant women was found as 22.96%, which shows that the vitamin B12 deficiency is important in the etiology of anemia as frequent as iron deficiency.