Abstract
GDP‐mannose transporters (Gmt) carry nucleotide sugars from the cytosol across the Golgi apparatus membrane in various eukaryotic organisms. Some fungal species like Saccharomyces cerevisiae express a single gmt, while others including A. nidulans express two (gmtA and gmtB). GmtA and GmtB display a punctate pattern of distribution indicative of localization within the Golgi apparatus. Gmt in S. cerevisiae localizes to the Golgi as well, and proper localization is dependent on oligomerization. Here we report progress on determining if GmtA and GmtB form oligomers and the preferred combinations of GmtA and GmtB for Golgi localization. In addition, C‐ and N‐ terminal truncated versions of GmtA and GmtB were created in order to designate regions responsible for Golgi localization and possible oligomer formation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
