Abstract

Background: Recombinant human G-CSF hastens neutrophil recovery following hematopoietic stem cell transplantation (HSCT), thus accelerating engraftment.The optimal timing for use of G-CSF in conjunction to HSCT needs to be established.We present our data on effects of adding an extra dose of G-CSF (filgrastim 5 micro gm/kg) on day -1 of HSCT. Patients and Methods: Forty three consecutive patients who underwent HSCT in one year period were given G-CSF on day +1 (day before stem cell infusion) in addition to the regular doses from day +1 till engraftment.

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